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DefenAge

DefenAge PRO 360-Rejuvenation Nail Root Serum

AVAILABLE IN SPA ONLY

Authorized Physician Reseller

Getting to the Root of Healthy-Looking Nails.

What it is

360-Rejuvenation Nail Root Serum is a luxury nail and cuticle serum designed to improve the visible appearance and overall condition of the nails and surrounding skin.

As nails age, they can appear thinner, more fragile, and less uniform in texture. Daily activities, lifestyle habits, and environmental exposure can all affect how nails look and feel over time. This lightweight serum is formulated to help support a healthier-looking nail and cuticle area with consistent use.

  • The 360-Rejuvenation Nail Root Serum is designed to care for the nail and nail-adjacent skin at the base of the nail, helping maintain a smooth, hydrated, and well-groomed appearance.

What It Does

  • Visibly improves the appearance of the nails and surrounding skin
  • Helps nails look smoother and more uniform
  • Supports the look of stronger, healthier nails
  • Hydrates and conditions nails and cuticles
  • Helps maintain a polished, well-cared-for nail appearance
  • Provides antioxidant support to help protect against environmental stressors

Why It's Different

  • Formulated with DefenAge’s proprietary Defensin-based technology, designed for cosmetic nail and cuticle care.
  • Features a thoughtfully curated blend of high-performing cosmetic ingredients, including Tara tree fruit extract, niacinamide, biotin, squalene, and amino acids
  • Lightweight, fast-absorbing serum texture suitable for daily useDelivers multiple cosmetic nail-care benefits in one easy step

.22 fl oz

How To Use

AM | PM DIRECTIONS:

Twice daily, in the morning and evening, using the built-in brush, apply 1-2 pumps of the serum on all the nails and on the skin all around the nails on both hands. Push the button of the bottle to release a pump of the serum on top of the brush and then distribute the serum across all the nails and skin around the nails. Start with the first (distal) phalange, and then brush the serum toward nail end. Ensure the serum is distributed to the skin surrounding all sides of the nail. Leave on serum for at least 30 minutes or overnight. Okay to use on finger and toe nails.

Key Ingredients

Age-Repair Defensins® PRO | Serum Level | DefenAge Exclusive: trigger nail-producing cells to revitalize nail

Defensins are natural molecules known to awaken dormant regenerative cells in our body. Multiple studies demonstrated their tremendous ability in helping our body make beautiful skin, hair, and nails. DefenAge contains an identical copy of human defensins made via biosynthesis; defensins are exclusive to DefenAge.

Methionine: nail strength

Methionine is an essential amino acid. It is a crucial building block of the nail.

Tara Tree Fruit Extract: protection, strengthening & beautifying

Caesalpinia Spinosa (Tara) Fruit Extract is an outstanding natural antioxidant, shown to be effective in protecting the nails and their keratin structure from damaging free radicals that can be caused by environmental stress, UV light, and harsh chemicals.

Vitamin B Complex | Niacinamide, Panthenol & Biotin: hydration • circulation • keratin

Vitamins B3 (niacinamide), B5 (panthenol), and B7 (biotin) are vital components of the nail-supporting system. The vitamins in this complex repair the natural moisturization of the nail and surrounding skin, revive oxygen supply, and activate nail keratin.

Fine Blend of Soothing and Calming Ingredients: addresses Inflamm-aging • calms nail environment

This formula is infused with a powerful and concentrated composition of soothing and calming botanical molecules, including extract from the flowers of ‘love in a puff’, a medical plant known as a cortisone-free alternative, Epigallocatechin Gallatyl Glucoside, a water-soluble form of one of the most active molecules found in green tea, and black currant seed extract.

Full Ingredient List

DOES NOT CONTAIN: Abrasives, aluminum salts, animal-derived ingredients, BPA, BHT/BHA, chemical sunscreens (oxybenzone, avobenzone, and octinoxate), coal tar, colorants, formaldehyde-releasing agents, formaldehydes, fragrance, gluten ingredients (no wheat, oats, barley), human-derived ingredients, hydroquinone, irritating acids, mineral oil, oxybenzone, parabens, paraffin, PEGs, petrolatum, phthalates, polyethylene and polypropylene (microbeads), propylene glycol, retinyl palmitate, silicones, sodium laureth sulfate, sodium lauryl sulfate, strong emulsifiers, sulfates (SLS and SLES), talc, toluene, triclocarban, triclosan, triethanolamine. Not tested on animals.

FULL INGREDIENT LIST: Water (Aqua), Panthenol, Niacinamide, Pentylene Glycol, Squalane, Ricinus Communis (Castor) Seed Oil, Octyldodecanol, Glyceryl Stearate Citrate, Alpha-Defensin 5, Beta-Defensin 3, Biotin, Caesalpinia Spinosa Fruit Pod Extract/Caesalpinia Spinosa Fruit Extract, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Helianthus Annuus (Sunflower) Sprout Extract, Helianthus Annuus Seed Oil Unsaponifiables, Helianthus Annuus Seed Oil, Ribes Nigrum Seed Oil, Rosmarinus Officinalis Leaf Extract, Leuconostoc/Radish Root Ferment Filtrate, Methionine, Epigallocatechin Gallatyl Glucoside, Phospholipids, Tocopherol, Tocopheryl Acetate, Ubiquinone, l-Alanyl-l-Glutamine, Polyglyceryl-3 Stearate, Hydrogenated Lecithin, Phytic Acid, Caprylic/Capric Triglyceride, Pistacia Lentiscus Gum, Polyacrylate Crosspolymer-6, Phenoxyethanol, Albumin, Sodium Benzoate, Potassium Sorbate, Propylene Glycol, Sodium Chloride.

FAQ

WHERE DOES THE ODOR COME FROM?

The 360-Rejuvenation Nail Root Serum does not contain fragrance or chemicals to absorb its organic scent. The odor you are experiencing is the natural scent of key performance ingredients. The "smelliest" one being an essential amino acid, called Methionine. It is crucial to keep our nails strong, therefore our scientists added it to the 360-Rejuvenation Nail Room Serum.

*This amino acid is also taken as a food supplement*